Hope in Action

Donations to Date

$0

Projects Funded

0

A world without cancer starts here, and it begins now.

What began as a bike ride in 2010 has evolved into a dynamic community mobilized for change, fueled by hope and united in our commitment to curing cancer.

100% of the dollars raised by the Pedal the Cause community - over $51 million - seed, speed, and lead cutting-edge cancer research at Siteman Cancer Center and Siteman Kids at St. Louis Children's Hospital. This transformational investment seeds promising research ideas and speeds innovation, bringing groundbreaking treatments from concept to lab to patient at an unprecedented speed. But our impact doesn't stop there. By investing in the brightest minds and nurturing the talent to lead this transformational research, we are planting the seeds for a future without the burden of cancer.

Give now, knowing 100% of your gift will fund transformational cancer research. Every penny.

DONATE

THE EVENT: September 20 & 21, 2025

Join is on the road the end cancer as a rider, on a spin bike, as a virtual Inspired fundraiser, a volunteer or a Kids Challenger. At Pedal the Cause, there is something for everyone at every ability and skill level!

GET INVOLVED

PEDAL THE CAUSE IMPACT

Pedal the Cause is a community of like-minded individuals with one goal: to fund the cutting-edge research that will one day end cancer.

15 Year Impact Report

14:1 ROI

For every $1 Pedal the Cause donates to cancer research an additional $14 is obtained (on average) in outside funding, resulting in over half a billion dollars in leveraged funds.

2025 Featured fighters

Kevin Lemp

Head & Neck Cancer Research Team

Breakthrough in Pediatric AML

Dr. Jeff Bednarski, pediatric hematologist and oncologist at Siteman Kids at St. Louis Children's Hospital talks about his Phase II Clinical Trial using NK Cells (Natural Kills Cells) to treat kids with acute myeloid leukemia (AML).

Personalized Vaccines

Dr. Timothy Eberlein, Director of the Siteman Cancer Center, explains the role Pedal the Cause has played in the development of personalized vaccines for breast and other cancers. Pedal the Cause has funded this research since 2013.

Cancer Disparities

Dr. Timothy Eberlein, Director of the Siteman Cancer Center, discusses the success of the program they created for the elimination of cancer disparities which was unique among all the NCI centers at the time of creation and Pedal's role in funding the program.

Our research is creating new treatments and standards of care that are being adopted across the country. Funding from our partner, Pedal the Cause, has been integral to the success of Siteman Cancer Center.

Dr. Timothy Eberlein
Director of Siteman Cancer Center

We are using a novel immune therapy (“Natural Killer Cells”) to treat leukemia in children and are the only cancer center providing this therapy. Funding from Pedal the Cause made this possible and is providing new hope!

Dr. Jeff Bednarski
Pediatric Hematologist/Oncologist at St. Louis Children’s Hospital

What Pedal the Cause did for us was to bring the acceleration we needed to take it to the clinic. And that was wonderful, because today there is hope for many patients.

Dr. Sam Achilefu
Siteman Cancer Center, inventor of cancer detection goggles

Harnessing the power of the immune system has improved our ability to fight pancreatic cancer. Pedal the Cause has increased our collaboration across disciplines leading to innovative team science and numerous clinical trials.

Dr. William Hawkins
Physician Scientist at Siteman Cancer Center

The funding from Pedal the Cause is a pillar of my lab. I don’t think my lab would exist without this funding.

Dr. Priyanka Verma
Siteman Cancer Center

Pediatric cancer researchers get 4% of the NIH cancer funding, so on we really depend on philanthropic giving, like Pedal the Cause, to do this research and make an impact on kids with cancer.

Dr. Maggie Ferris
Pediatric Hematologist/Oncologist at St. Louis Children’s Hospital

    Learn more about impact of Pedal the Cause dollars

    Funded Research Projects

    Pedal the Cause funded research is saving lives around the world
    Learn More

    Pedal the Cause Researchers

    Pedal the Cause funds the recruitment of top talent to lead new cancer research labs at our beneficiaries.
    Learn More

    Beneficiaries

    Siteman Cancer Center & Siteman Kids at St. Louis Children’s Hospital are ranked among the top tier cancer centers in the nation.
    Learn More