Four New Pediatric Cancer Research Projects Funded by Pedal the Cause

May 7, 2024

Pedal the Cause is proud to announce the funding of four new pediatric cancer research projects at Washington University School of Medicine in St. Louis to benefit Siteman Kids at St. Louis Children’s Hospital. These four projects focus on advancing immunotherapies (CAR-T cells and NK cell therapies), developing therapies to target genetic mutations involved in pediatric cancers and creating a new Chat-GPT language model. In 2023, Pedal the Cause donated $1,501,174 to St. Louis Children’s Hospital Foundation to fund research projects at Washington University to advance pediatric cancer research and improve outcomes for patients at Siteman Kids at St. Louis Children’s Hospital and elsewhere.

“The breakthroughs enabled through the ongoing support of Pedal the Cause are providing answers for children and families living with cancer and fueling hope that earlier, more accurate diagnoses will lead to improved outcomes,” said Jorge Di Paola, MD, division chief of pediatric hematology-oncology at Washington University School of Medicine. “These investments allow our researchers to develop their proof of concept and critical data that they can use in their application to receive a greater share of the federal funds allocated to pediatric cancer research each year. We are profoundly grateful for the support from Pedal the Cause.”

This year, Pedal the Cause, presented by Edward Jones, returns for its 15 year of raising critical funds for adult and pediatric cancer research, with an exciting lineup of cycling and community events. On September 21 and 22, thousands will gather in St. Charles for a celebratory weekend of pedaling, community, festivities and family fun. Registration is now open for bike riders of all levels, spinners, virtual fundraisers, Kids Challengers and volunteers with a passion to create a world without cancer.

Pedal the Cause is one of the top-ten largest cause-related cycling events in the country, having donated over $45.8 million since 2010 to fund the best and brightest ideas in cancer research. All – 100 percent – of participant-raised funds support innovative cancer research at Washington University School of Medicine, aimed at benefiting Siteman Cancer Center and Siteman Kids at St. Louis Children’s Hospital. This research is producing new treatments and cures for cancer for patients in St. Louis and around the world. To date, Pedal the Cause has funded 223 cancer research projects – 171 adult and 52 pediatric.

Read about the newly funded pediatric projects here:

Registration for 2024 is now open at