Ride Weekend
Thousands of Participants.
Two Days. One Goal.
A World Without Cancer.
We’re gearing up for our 16th year of creating a world without cancer on Saturday, September 20 and Sunday, September 21 at the Family Arena in St. Charles. Celebrate on Saturday, ride on Sunday and share the unparalleled Pedal the Cause experience with our community!
Pedal the Cause 2025 will feature 7 new course options (6 road and 1 gravel), our signature Spin Zone, our Inspired virtual participation option and our Kids Challenge.
Saturday
September 20, 2025
Food & drink from the St. Louis region's top restaurants and community building
Live music from Retro Nerds
6:30 p.m.
Living Proof Photo & Processional
Inspirational Program and fireworks
Sunday
September 21, 2025
Breakfast Bar, Late Packet Pickup, Bike Maintenance and Rental
Post-Ride lunch and celebration
11 a.m. – 3 p.m.
Live music from Yacht Rockers
Watch our 2024 Event Video

100% of participant-raised donations seed, speed and lead cutting-edge cancer research at Siteman Cancer Center & Siteman Kids at St. Louis Children’s Hospital.