Impact

Donations to Date

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Projects Funded

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We all have a reason to fight for a world without cancer.

Cancer will strike one in two men and one in three women in their lifetimes. One in 285 children will be diagnosed with cancer before their 20th birthday.

With so many affected by the disease, we all have a personal reason to fight for a world without cancer and to improve the treatment options, outcomes and quality of life for those battling all cancers. The need for funding innovative research has only intensified, as large federal grants are only awarded to already proven concepts.

100% of the dollars raised by the Pedal the Cause community provide direct funding for cancer research, cancer discovery grants and clinical translational care not currently eligible for federal funds. Following the “venture capital” model seeding new ideas at our beneficiaries, Pedal the Cause dollars allow for proof of concept and cultivation of critical data. These burgeoning projects often lead to incremental successes that garner large external grants, which have produced groundbreaking treatments, clinical trials, preventions and early detection diagnostics.

13:1 ROI

For every $1 Pedal the Cause donates to cancer research an additional $13 is obtained (on average) in outside funding, resulting in over $595 million in leveraged funds.

2024 Impact shorts

Dr. Jeff Bednarski

Dr. Jeff Bednarski, pediatric hematologist and oncologist at Siteman Kids at St. Louis Children's Hospital talks about his Phase II Clinical Trial using NK Cells (Natural Kills Cells) to treat kids with acute myeloid leukemia (AML). Pedal the Cause has funded Dr. Bednarski six times since 2012, including the initial research and Phase I Trial of this study. "This work doesn't happen without donations," said Bednarski. "Donating to Pedal the Cause, supporting the world that's being done at Siteman and Siteman Kids is making a difference."

Dr. Timothy Eberlein

Dr. Timothy Eberlein, Director of the Siteman Cancer Center, explains the role Pedal the Cause has played in the development of personalized vaccines for breast and other cancers. Pedal the Cause has funded this research since 2013. "When you stop and think about it, in a very short period of time the impact Pedal the Cause has had, is really unique," said Eberlein. "And the contributions that we have made that are paradigm shifting contributions are also pretty unique."

Dr. Ryan Fields

Dr. Ryan Fields, Chief of Surgical Oncology at Siteman Cancer Center, talks about the momentum created when Pedal the Cause funds new science. Pedal is at the forefront of taking these innovative ideas into the future, helping them secure larger funding from other agencies like the NIH. "It's been such an incredible journey that we've been on together, and we still have a long way to go," says Dr. Fields. "We wouldn't be able to continue this journey as successfully as we have, or reach where we want to go, without Pedal the Cause."

Pedal the Cause is a community of like-minded individuals with one goal: to fund the cutting-edge research that will one day end cancer.

View Our 2023 Impact Report

Our research is creating new treatments and standards of care that are being adopted across the country. Funding from our partner, Pedal the Cause, has been integral to the success of Siteman Cancer Center.

Dr. Timothy Eberlein
Director of Siteman Cancer Center

We are using a novel immune therapy (“Natural Killer Cells”) to treat leukemia in children and are the only cancer center providing this therapy. Funding from Pedal the Cause made this possible and is providing new hope!

Dr. Jeff Bednarski
Pediatric Hematologist/Oncologist at St. Louis Children’s Hospital

What Pedal the Cause did for us was to bring the acceleration we needed to take it to the clinic. And that was wonderful, because today there is hope for many patients.

Dr. Sam Achilefu
Siteman Cancer Center, inventor of cancer detection goggles

Harnessing the power of the immune system has improved our ability to fight pancreatic cancer. Pedal the Cause has increased our collaboration across disciplines leading to innovative team science and numerous clinical trials.

Dr. William Hawkins
Physician Scientist at Siteman Cancer Center

The funding from Pedal the Cause is a pillar of my lab. I don’t think my lab would exist without this funding.

Dr. Priyanka Verma
Siteman Cancer Center

Pediatric cancer researchers get 4% of the NIH cancer funding, so on we really depend on philanthropic giving, like Pedal the Cause, to do this research and make an impact on kids with cancer.

Dr. Maggie Ferris
Pediatric Hematologist/Oncologist at St. Louis Children’s Hospital