Donations to Date


Projects Funded


We all have a reason to fight for a world without cancer.

Cancer will strike one in two men and one in three women in their lifetimes. One in 285 children will be diagnosed with cancer before their 20th birthday.

With so many affected by the disease, we all have a personal reason to fight for a world without cancer and to improve the treatment options, outcomes and quality of life for those battling all cancers. The need for funding innovative research has only intensified, as large federal grants are only awarded to already proven concepts.

100% of the dollars raised by the Pedal the Cause community provide direct funding for cancer research, cancer discovery grants and clinical translational care not currently eligible for federal funds. Following the “venture capital” model seeding new ideas at our beneficiaries, Pedal the Cause dollars allow for proof of concept and cultivation of critical data. These burgeoning projects often lead to incremental successes that garner large external grants, which have produced groundbreaking treatments, clinical trials, preventions and early detection diagnostics.

13:1 ROI

For every $1 Pedal the Cause donates to cancer research an additional $13 is obtained (on average) in outside funding, resulting in over $595 million in leveraged funds.

2024 Impact shorts

Dr. Jeff Bednarski

Dr. Jeff Bednarski, pediatric hematologist and oncologist at Siteman Kids at St. Louis Children's Hospital talks about his Phase II Clinical Trial using NK Cells (Natural Kills Cells) to treat kids with acute myeloid leukemia (AML). Pedal the Cause has funded Dr. Bednarski six times since 2012, including the initial research and Phase I Trial of this study. "This work doesn't happen without donations," said Bednarski. "Donating to Pedal the Cause, supporting the world that's being done at Siteman and Siteman Kids is making a difference."

The Drier Family

When Victoria faced a cancer diagnosis at age 16, the Drier family, along with the doctors at St. Louis Children's Hospital, came together to explore every cutting-edge option for treatment. Pedal the Cause's Executive Director David Drier and his family share the inspiring story behind their passion to create a world without cancer.

Team Victoria's Profile

Ted Wheeler

Meet Ted Wheeler. Despite many of his beloved family members succumbing to cancer throughout his life, Ted’s family didn’t discuss the disease until they were faced with a loss. He knows this is all too common the black community and is here to change that. Ted was diagnosed with prostate cancer in 2021, and now uses his own diagnosis as an opportunity to have tough conversations with loved ones about prevention and early detection. Through his connection to Pedal the Cause, he hopes to inspire others to face their fears and advocate for their own health.

Pedal the Cause is a community of like-minded individuals with one goal: to fund the cutting-edge research that will one day end cancer.

View Our 2023 Impact Report

Our research is creating new treatments and standards of care that are being adopted across the country. Funding from our partner, Pedal the Cause, has been integral to the success of Siteman Cancer Center.

Dr. Timothy Eberlein
Director of Siteman Cancer Center

We are using a novel immune therapy (“Natural Killer Cells”) to treat leukemia in children and are the only cancer center providing this therapy. Funding from Pedal the Cause made this possible and is providing new hope!

Dr. Jeff Bednarski
Pediatric Hematologist/Oncologist at St. Louis Children’s Hospital

What Pedal the Cause did for us was to bring the acceleration we needed to take it to the clinic. And that was wonderful, because today there is hope for many patients.

Dr. Sam Achilefu
Siteman Cancer Center, inventor of cancer detection goggles

Harnessing the power of the immune system has improved our ability to fight pancreatic cancer. Pedal the Cause has increased our collaboration across disciplines leading to innovative team science and numerous clinical trials.

Dr. William Hawkins
Physician Scientist at Siteman Cancer Center

The funding from Pedal the Cause is a pillar of my lab. I don’t think my lab would exist without this funding.

Dr. Priyanka Verma
Siteman Cancer Center

Pediatric cancer researchers get 4% of the NIH cancer funding, so on we really depend on philanthropic giving, like Pedal the Cause, to do this research and make an impact on kids with cancer.

Dr. Maggie Ferris
Pediatric Hematologist/Oncologist at St. Louis Children’s Hospital